Journals

Author

James Eapen

Categories

Title Publication date Date added
Systematic comparison of single-cell and single-nucleus RNA-sequencing methods Apr 6, 2020 Jun 1, 2020
Evaluation of relational and NoSQL database architectures to manage genomic annotations Oct 31, 2016 Jun 10, 2021
Interplay between the cancer genome and epigenome Mar 28, 2013 May 17, 2022
The diverse roles of DNA methylation in mammalian development and disease Aug 9, 2019 May 18, 2022
DNA methylation loss in late-replicating domains is linked to mitotic cell division Apr 2, 2018 May 19, 2022
Defining cell types and states with single-cell genomics Oct 25, 2015 May 23, 2022
The evolving concept of cell identity in the single cell era Jun 27, 2019 May 24, 2022
RNA velocity of single cells Aug 8, 2018 May 25, 2022
Generalizing RNA velocity to transient cell states through dynamical modeling Aug 3, 2022 May 25, 2022
RNA velocity—current challenges and future perspectives Aug 26, 2021 May 26, 2022
Clear cell and endometrioid carcinomas: are their differences attributable to distinct cells of origin? Aug 7, 2017 May 27, 2022
Lineage tracing in human tissues Apr 12, 2022 Jun 6, 2022
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma Aug 8, 2019 Jun 28, 2022
A single-cell landscape of high-grade serous ovarian cancer Jun 22, 2020 Jul 1, 2022
Non-genetic determinants of malignant clonal fitness at single-cell resolution Dec 8, 2021 Jul 5, 2022
Transition states and cell fate decisions in epigenetic landscapes Sep 12, 2016 Jul 19, 2022
What is a cell type and how to define it Jul 21, 2022 Jul 22, 2022
DREISS: Using State-Space Models to Infer the Dynamics of Gene Expression Driven by External and Internal Regulatory Networks Oct 19, 2016 Aug 9, 2022
Epigenetic regulation of cell fate reprogramming in aging and disease: A predictive computational model Mar 15, 2018 Aug 31, 2022
Control of cell state transitions Sep 14, 2022 Sep 15, 2022
Multi-omic single-cell velocity models epigenome–transcriptome interactions and improves cell fate prediction Oct 13, 2022 Oct 17, 2022
Cell division drives DNA methylation loss in late-replicating domains in primary human cells Nov 8, 2022 Nov 18, 2022
Barcode-free prediction of cell lineages from scRNA-seq datasets Sep 20, 2022 Nov 21, 2022
Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq Apr 11, 2022 Dec 2, 2022
Defining ancestry, heritability and plasticity of cellular phenotypes in somatic evolution Dec 30, 2022 Jan 4, 2023
Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution Sep 4, 2009 Mar 10, 2023
The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids Dec 8, 2015 Mar 13, 2023
Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention Dec 10, 2014 Mar 13, 2023
The triumphs and limitations of computational methods for scRNA-seq Jun 21, 2021 Mar 16, 2023
Transcriptome-wide noise controls lineage choice in mammalian progenitor cells May 21, 2008 Mar 20, 2023
Cell Fate Decision as High-Dimensional Critical State Transition Jan 9, 2017 Mar 23, 2023
SEACells infers transcriptional and epigenomic cellular states from single-cell genomics data Mar 27, 2023 Mar 30, 2023
Identifying an ovarian cancer cell hierarchy regulated by bone morphogenetic protein 2 Nov 30, 2015 Apr 6, 2023
Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells Jul 18, 2014 May 27, 2023
Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma Nov 26, 2019 Jul 10, 2023
Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia Jan 9, 2023 Jul 11, 2023
The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells Feb 10, 2020 Jul 12, 2023
MATCHER: manifold alignment reveals correspondence between single cell transcriptome and epigenome dynamics Jul 24, 2017 Aug 19, 2023
Precise identification of cell states altered in disease using healthy single-cell references Oct 12, 2023 Mar 13, 2024
Separating measurement and expression models clarifies confusion in single-cell RNA sequencing analysis May 24, 2021 May 10, 2024
Quantifying cell-state densities in single-cell phenotypic landscapes using Mellon Jun 18, 2024 Sep 18, 2024
Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans Sep 9, 2020 Invalid Date
Cellular senescence and failure of myelin repair in MS Dec 1, 2020 Feb 26, 2020
Cellular senescence and Alzheimer disease: the egg and the chicken scenario Jun 29, 2020 Nov 2, 2020
Cellular Senescence in Neurodegenerative Diseases Feb 11, 2020 Nov 9, 2020
Telomere Attrition in Neurodegenerative Disorders Jul 15, 2020 Nov 18, 2020
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor Dec 2, 2008 Dec 10, 2020
Cellular senescence: Defining a path forward Oct 31, 2019 Dec 11, 2020
Ageing as a risk factor for neurodegenerative disease Oct 15, 2019 Dec 17, 2020
Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer’s Disease Sep 16, 2020 Dec 17, 2020
Single-cell transcriptomic analysis of Alzheimer’s disease May 1, 2019 Dec 22, 2020
Four faces of cellular senescence Feb 21, 2011 Jan 20, 2021
Vascular Cell Senescence Contributes to Blood–Brain Barrier Breakdown Feb 16, 2021 Jan 20, 2021
Astrocyte Senescence and Alzheimer’s Disease: A Review Jun 9, 2020 Jan 20, 2021
Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts Aug 11, 2020 Feb 11, 2021
The Cellular Phase of Alzheimer’s Disease Feb 11, 2015 Feb 15, 2021
Astrocyte senescence promotes glutamate toxicity in cortical neurons Jan 16, 2020 Mar 8, 2021
Loss-of-function of p53 isoform Δ113p53 accelerates brain ageing in zebrafish Feb 4, 2021 Mar 12, 2021
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease Apr 21, 2018 Mar 16, 2021
Epigenetic Basis of Cellular Senescence and Its Implications in Aging Nov 24, 2017 Mar 17, 2021
Cellular senescence: Immunosurveillance and future immunotherapy May 1, 2018 Mar 17, 2021
A multidimensional systems biology analysis of cellular senescence in aging and disease Apr 7, 2020 Mar 18, 2021
Cellular Senescence and Iron Dyshomeostasis in Alzheimer’s Disease Jun 19, 2019 Mar 18, 2021
Molecular Mechanism for Age-Related Memory Loss: The Histone-Binding Protein RbAp48 Aug 28, 2013 Mar 29, 2021
Transcriptome signature of cellular senescence Jun 28, 2019 Apr 19, 2021
Big Data Analysis of Genes Associated With Neuropsychiatric Disorders in an Alzheimer’s Disease Animal Model Jun 15, 2018 Apr 21, 2021
Impaired immune surveillance accelerates accumulation of senescent cells and aging Dec 21, 2018 Apr 22, 2021
Inflammation, A beta deposition, and neurofibrillary tangle formation as correlates of Alzheimer’s disease neurodegeneration Oct 1, 1996 Apr 26, 2021
Early onset senescence and cognitive impairment in a murine model of repeated mTBI May 8, 2021 May 14, 2021
An aged immune system drives senescence and ageing of solid organs May 12, 2021 May 19, 2021
Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10 Jul 15, 2014 Jun 4, 2021
The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype Apr 28, 2021 Jun 18, 2021
Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain Mar 1, 2021 Jul 2, 2021
Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span Jul 30, 2021 Sep 1, 2021
Stem-Like Epithelial Cells Are Concentrated in the Distal End of the Fallopian Tube: A Site for Injury and Serous Cancer Initiation Oct 22, 2012 Aug 24, 2022
Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes Apr 12, 2021 Invalid Date
Evidence of the Cellular Senescence Stress Response in Mitotically Active Brain Cells — Implications for Cancer and Neurodegeneration May 7, 2021 Invalid Date
Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition Nov 30, 2020 Jun 25, 2021
The Genetic Landscape of Alzheimer’s disease Nov 2, 2020 Invalid Date
Genetics of Alzheimer’s disease: where we are, and where we are going Nov 2, 2020 Invalid Date
When does Alzheimer’s disease really start? The role of biomarkers Nov 10, 2020 Invalid Date
Genetic meta-analysis of diagnosed Alzheimer’s disease Dec 8, 2020 Invalid Date
Alzheimer’s Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation Feb 12, 2021 Invalid Date
Senescence as an Amyloid Cascade: The Amyloid Senescence Hypothesis Dec 20, 2020 Invalid Date
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